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Dr. Don Colbert, MD

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Dr. Colbert's Healthy Gut Zone System
Gut & Digestion Healthy Living Articles

Dr. Colbert’s Healthy Gut Zone System

Don Colbert, MD
Written by Don Colbert, MD, board-certified in family practice and in anti-aging and integrative medicine for more than 25 years
Last reviewed and updated: October 17, 2026

Did you know there’s one system in your body that’s responsible for the health of all other systems? Sure, if your nervous system or cardiovascular system fails, the whole body fails. However, there’s one system that functions to maintain the health of all other crucial organs. This one system is the digestive system. Your digestive health is paramount to your entire body’s health, and specifically your brain’s health.

Unfortunately, it’s estimated that 60-70 million Americans suffer from chronic digestive issues each year (1). Some are severe. Some are more minor. All impede everyday life to some extent and affect every other system in the body.

It’s for this reason that Dr. Colbert has created an amazing system to help you care for your digestive health: Dr. Colbert’s Healthy Gut Zone System. This complete kit includes the best probiotics available, a two-fiber supplement powder for complete digestive health, and Dr. Colbert’s Gut Zone book.

With the Healthy Gut Zone System, you’ll learn how digestive health affects your entire body and what you can do to keep yours in top-notch shape!

Digestive Health, Brain Health & Beyond

Amazingly, your digestive health has direct implications for your brain health. In fact, it’s now known that:

  • Gut inflammation promotes brain inflammation and declining function
  • An unhealthy digestive tract promotes illness in other parts of the body
  • Healing your gut can reduce brain fog, increase alertness, support youthful memory, and energize the body and brain
  • Immune function is dependent on a healthy digestive tract

Healthy digestion is first responsible for nourishing your body, from your hair to your toes. What’s more, there is an incredible gut-brain connection that impacts your brain health directly. In fact, your digestive tract is home to 75% of your immune system. The health of your brain depends on strong immunity and a healthy gut-brain connection!

Are you convinced? Ready to take care of your digestive health above all else? Here are 5 steps you can take today to optimize digestive health and therefore, whole-body health with Dr. Colbert’s Healthy Gut Zone System.

5 Steps to Optimal Digestive Health

1. Take Care of the Good Bacteria

Forty trillion. This is the number of bacteria in your body. Most are in your intestines. And, most are there to help you.

It’s time to start helping them. How?

It’s simple, really. The first thing to do is to replenish and fortify your healthy bacteria with probiotic supplements and foods.

Within Dr. Colbert’s Healthy Gut Zone System, you’ll receive Dr. Colbert’s Zone Biotics. Zone Biotics is a probiotic supplement that contains live, viable probiotic bacteria in pill form. It is specifically beneficial to modern-day humans since we have many food-supply, environmental, and chemical compounds that harm our digestive tracts and bacteria.

Both anecdotal reports and studies show that probiotics help acute digestion symptoms. They can also produce beneficial effects on the bacteria in the gut (2). What’s more, they can affect other health issues within the body as they improve digestion comfort, nutrient absorption and microbiota (3, 4, 5).

In addition, Dr. Colbert’s Gut Zone Book emphasizes healthy foods you can consume to fortify your digestive tract’s healthy bacteria. These include Divine Health® Fermented Green Supremefood, plain yogurt, kimchi, sauerkraut, kefir, kombucha, tempeh, and more.

Don’t leave your healthy bacteria to fend for themselves. Fortify them with probiotics each day.

2. Fortify Your Digestive Tract with Fiber

Next, you can fortify your digestive tract with fiber. Dr. Colbert’s Keto Zone® Fiber Zone is included in the Healthy Gut Zone System.

Dr. Colbert’s Keto Zone® Fiber Zone is a delicious fiber powder specially formulated using 2 of the most powerful, important fibers available. 

First, it contains psyllium husk. Psyllium husk is made of both soluble (70%) and insoluble fibers (30%).  This means twice the benefits. It acts as a prebiotic, feeding and fortifying healthy gut bacteria. Its insoluble fiber passes through the digestive tract, providing bulk and softness to stools. This encourages digestive health, reduced inflammation, and a healthy gut-brain connection (6).

Next, Fiber Zone contains inulin. Inulin is a prebiotic fiber. Like psyllium, it feeds the healthy bacteria and cells in our digestive tracts, making them stronger and healthier (7). 

Together, these fibers work to reduce hunger cravings, support healthy digestion, encourage optimal weight, support bone health and optimize the gut-brain connection (8).

In addition, following Dr. Colbert’s Gut Zone Book, eat healthy high fiber and prebiotic foods. These include berries, artichokes, asparagus, broccoli, greens, onions, garlic, leeks, cacao, flaxseeds, hemp heart seeds, nuts, and more.

3. Nourish with Collagen

Collagen is another great food for your digestive health!

In fact, collagen supports healthy digestion, joint health, vibrant skin, healthy weight, and more!

In particular, those who suffer from leaky gut syndrome can find relief by adding collagen to their diets. With this digestive issue, toxins, allergens and large particles are able to pass from your gut into your bloodstream, causing negative reactions. Collagen can help fortify connective tissue in the protective lining of the digestive tract. It heals it and helps it seal out the offending particles. Further, it supports better digestive health in those who suffer from inflammatory digestive issues, acid reflux, and more (9).

Keto Zone® Collagen Powder is a great source of collagen. It is enzymatically hydrolyzed, or predigested, for effortless digestion and full absorption into the body. It is derived from chicken and marine peptides, and contains Types I, II, and III collagen. This combination of collagen supports the formation of elastin in the body, which is critical in fighting against wrinkles and sagging skin. 

4. Avoid Harmful Substances

Did you know some substances you consume actually harm digestive health? Some foods, drinks, and environmental contaminants harm or destroy digestive cells, healthy bacteria, and more. These include:

  • Sugar: Sugar can harm the digestive tract in a few ways. First, it promotes the growth of harmful Candida albicans which can lead to leaky gut and other digestive issues (10). Next, in animal studies, high-sugar diets increased gut permeability, degraded healthy gut barriers, increased spleen weight, and increased the inflammatory immune response (11).
  • Man-Made Artificial Sweeteners: Chemical artificial sweeteners have been widely used in “diet foods.” Unfortunately, they can have negative effects on gut bacteria.   Animal and human studies have shown that aspartame, saccharin, sucralose, and other artificial sweeteners can impair gut bacteria (12) allowing other microbes to take over (13). If you use sugar substitutes, make sure they are natural ones like sugar alcohols: xylitol is safe and does not seem to affect gut bacteria (13).
  • Antibiotics: In recent years, there has been a push to drastically reduce the use of antibiotics in humans and animals. Doctors have been urged to prescribe antibiotics only when necessary, and with much less frequency than in previous decades. The overuse of antibiotics has been shown to 1) hurt the gut by wiping out healthy bacteria, and 2) lead to antibiotic-resistant bacteria. In fact, the World Health Organization is also working to reduce the antibiotics that humans consume. It is recommending that routine antibiotic use in animals is stopped and reserved only when the animal is sick (14).
  • Alcohol: Unfortunately, alcohol, especially in large quantities, can negatively affect the bacteria colonies in the gut. In fact, many people who abuse alcohol have impaired nutrient absorption, poor digestion, and discomfort. When used in moderation, bacteria colonies can remain healthy. But, overuse of alcohol can destroy them (15).
  • Nicotine: Nicotine is harmful to digestive health. It has been associated with excess reflux, peptic ulcers, and a decrease in colon strength. What’s more, smokers experience higher Helicobacter pylori infections (16).

While you use the tools in Dr. Colbert’s Healthy Gut Zone System, you will learn to also avoid these compounds that harm your digestive system.

5. Be Active, Hydrate, and Reduce Stress

Your lifestyle choices make a difference in the health of your digestive system.

First, exercise can improve digestion. Movement and gravity help food naturally move through your intestines. On the other hand, a sedentary lifestyle actually harms the digestive system. Sitting for long stretches slows the natural movement of food through your intestines, which makes healthy digestion more difficult. Make sure to get up frequently and include physical activity each day to support healthy digestion.

Next, healthy digestion depends on the presence of fluids. Water helps break down food, lubricates the digestive tract, reduces constipation, and keeps your cells healthy. Make sure to drink water throughout each day.

Lastly, chronic stress can have a negative effect on digestion. In fact, chronic stress can decrease the blood flow to the intestines, slow nutrient absorption, and even change how the bacteria in your gut function. One way to reduce stress? In addition to daily de-stress strategies, make sure you stay hydrated! Dehydration is linked to elevated cortisol levels.

Watch: Leaky Gut Symptoms and How to Heal Your Gut Naturally

In this episode, Mary and I explain what causes leaky gut, from antibiotics and NSAIDs to processed carbs, the gut tests I use with patients, and the daily routine I follow to support a healthy gut lining.

Bottom Line

You can improve your digestive health, support your entire body, and improve brain function, alertness and health starting today! Join Dr. Colbert in his challenge to help the millions of Americans that suffer from digestive issues. Try Dr. Colbert’s Healthy Gut Zone System now and enjoy better digestion!

Frequently Asked Questions

What is included in the Healthy Gut Zone System?

The system brings together three tools: Zone Biotics, a daily probiotic; Fiber Zone, a fiber powder made with psyllium husk and inulin; and my book, The Healthy Gut Zone, which explains the foods, habits, and lifestyle steps that support a healthy digestive tract.

What are the signs of an unhealthy gut?

Common signs include bloating, gas, constipation or diarrhea, heartburn, and stomach discomfort after meals. Many people also notice fatigue, brain fog, skin flare-ups, or new food sensitivities. See your doctor promptly for blood in the stool, unexplained weight loss, or severe pain.

How long does it take to improve gut health?

Many people notice changes in their digestion within a few weeks of eating more fiber, adding fermented foods, and cutting back on sugar. Rebuilding a healthy microbiome and gut lining usually takes several months of consistent habits, so think of it as a lifestyle rather than a quick fix.

Should I take probiotics and fiber together?

Yes, they work well as a team. Probiotics add beneficial bacteria, and prebiotic fibers like psyllium and inulin feed those bacteria so they can thrive. Start with a small amount of fiber, increase slowly, and drink plenty of water to avoid gas and bloating.

Do artificial sweeteners hurt your gut?

They may. In a well-known 2014 study published in Nature, artificial sweeteners such as saccharin changed the gut bacteria of mice and some people in ways that worsened blood sugar control. I recommend natural options like stevia, monk fruit, or xylitol instead.

References

  1. National Institute of Diabetes and Digestive and Kidney Diseases. Digestive Diseases Statistics for the United States.
  2. National Center for Complementary and Integrative Health. Probiotics: Usefulness and Safety.
  3. Slavin J. Fiber and prebiotics: mechanisms and health benefits. Nutrients. 2013.
  4. Suez J, et al. Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature. 2014.

This article is for educational purposes only and is not medical advice. Talk with your own doctor before changing your diet, starting a supplement, or changing any medication. These statements have not been evaluated by the Food and Drug Administration. Products mentioned are not intended to diagnose, treat, cure, or prevent any disease.

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Don Colbert, MD, has been board-certified in family practice and in anti-aging and integrative medicine for more than 25 years. He is the medical director of the Divine Health Wellness Center, where he has treated more than 50,000 patients, and a New York Times bestselling author of books including The Seven Pillars of Health, What Would Jesus Eat?, Deadly Emotions and Keto Zone Diet, with more than ten million books sold. He hosts Dr. Colbert's Broadcast with his wife Mary and son Kyle, where faith meets functional medicine. He and Mary live in Orlando, Florida and Dallas, Texas.